产品详情 |
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Antigenic Specificity | RAPSN |
Clone | 1234 |
Host Species | Mouse |
Reactive Species | amphibian, chicken, fish, mouse, rat |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunofluorescence: 2 µg/mL, Western Blot: 0.5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RAPSN Monoclonal Antibody (1234). Nicotinic acetylcholine receptors (AChRs) are organized into high-density postsynaptic clusters at the motor endplate that are critical for efficient synaptic transmission. The organization of AChR's is carried out by the 43 kDa cytoplasmic protein rapsyn. Studies have indicated that mutations which impair the activity of rapsyn can lead to the formation of congenital myasthenic syndrome (CMS). CMS is characterized by poor development of the postsynaptic region. |
Immunogen | n/a |
Other Names | 43 kDa receptor-associated protein of the synapse, RAPsyn, Acetylcholine receptor-associated 43 kDa protein, 43 kDa postsynaptic protein |
Gene, Accession # | Entrez: 19400, 362161, 395986; Uniprot: O42393, P12672 |
Catalog # | MA1-746 |
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Order / More Info | RAPSN Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 11157973, 18420419, 9254666, 9556625, 9592096, 9647653 |
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