产品详情 |
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Antigenic Specificity | RARA |
Clone | Ralpha10 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | purified |
Size | 50 µg |
Concentration | lyophilized |
Applications | Immunocytochemistry: 1:10-1:200, Immunofluorescence: 1:10-1:200, Western Blot: 1:100-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RARA Monoclonal Antibody (Ralpha10). Retinoic acid, a metabolite of vitamin A, is necessary for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. Retinoic acid functions through its interaction with the nuclear protein, retinoic acid receptor (RAR). RAR belongs to the steroid and thyroid hormone superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. RAR exists as three major subtypes: alpha, beta and gamma. The corresponding gene for the the retinoic acid receptor alpha is NR1B1. |
Immunogen | n/a |
Other Names | RAR alpha, Acute Promelocytic Leukemia Breakpoint Cluster Region, NR1B1, RARA/PML Fusion Gene |
Gene, Accession # | Entrez: 19401, 24705, 5914; Uniprot: P10276, P11416 |
Catalog # | MA1-810A |
Price | |
Order / More Info | RARA Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 19332432 |
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