产品详情 |
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Antigenic Specificity | LRRFIP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 5 µg/mL, Western Blot: 0.5-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | LRRFIP2 Polyclonal Antibody. The leucine-rich repeat FLI-I-interacting protein 2 (LRRFIP2), like the related protein LRRFIP1, was identified in a yeast two-hybrid system through binding to the LRR domain of human FLI. It can activate the Wnt signaling pathway in cultured cells and is thought to be a component of the Wnt signaling pathway that modulates Wnt signaling through interactions with Disheveled to increase the cellular levels and transcription activity of beta-catenin. LRRFIP2 has recently been characterized as a positive regulator of the TLR4 signaling pathway for activating NF-kappa-B during the early host response to LPS stimulation through binding to the TLR adaptor protein MyD88, and that this interaction with MyD88 is governed |
Immunogen | n/a |
Other Names | HUFI-2; LRR FLII-interacting protein 2; leucine-rich repeat flightless-interacting protein 2 |
Gene, Accession # | Entrez: 301035, 71268, 9209; Uniprot: Q4V7E8, Q91WK0, Q9Y608 |
Catalog # | PA5-21115 |
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Order / More Info | LRRFIP2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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