| 产品详情 |
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| Antigenic Specificity | MRP5 |
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| Clone | M5II-54 |
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| Host Species | Rat |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 1 mL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay dependent., Immunocytochemistry: 1:20, Immunohistochemistry (Frozen): 1:20, Western Blot: 1:20 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MRP5 Monoclonal Antibody (M5II-54). ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopuri |
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| Immunogen | n/a |
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| Other Names | MRP5 |
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| Gene, Accession # | Entrez: 10057; Uniprot: O15440 |
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| Catalog # | MA1-35684 |
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| Price | |
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| Order / More Info | MRP5 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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