| 产品详情 |
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| Antigenic Specificity | Pc2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:500-1:2,000, Immunoprecipitation: 2-5 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Pc2 Polyclonal Antibody. CBX4 is a member of Drosophila Polycomb group gene family. The polycomb group (PcG) genes are essential for maintenance of proper expression patterns of developmental master regulators; changes in expression pf PcG proteins have been associated with cancer. CBX4 is a part of the cellular memory system responsible for the inheritance of gene activity by progeny cells. It participates in maintaining the transcriptionally repressive state of genes. CBX4 is part of acomplex that acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. CBX4 is an E3 SUMO-protein ligase which facilitates SUMO1 conjugati |
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| Immunogen | n/a |
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| Other Names | E3 SUMO-protein ligase CBX4; Chromobox protein homolog 4; Polycomb 2 homolog; Pc2; hPc2 |
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| Gene, Accession # | Entrez: 12418, 8535; Uniprot: O00257, O55187 |
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| Catalog # | A302-355A |
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| Price | |
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| Order / More Info | Pc2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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