产品详情 |
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Antigenic Specificity | Ephrin B1 |
Clone | 2D3E9 |
Host Species | Mouse |
Reactive Species | chicken, human |
Isotype | IgG1, kappa |
Format | purified |
Size | 50 µg |
Concentration | n/a |
Applications | ELISA: Assay Dependent, Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ephrin B1 Monoclonal Antibody (2D3E9). Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and |
Immunogen | n/a |
Other Names | EFL6, EFNB3, EPH related receptor transmembrane ligand ELK L3, EPH related receptor tyrosine kinase ligand 8, Ephrin B3, EPLG8, LERK8 |
Gene, Accession # | Entrez: 1947, 395896; Uniprot: O73612, P98172 |
Catalog # | 37-8100 |
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Order / More Info | Ephrin B1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 26479588, 28362857 |
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