产品详情 |
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Antigenic Specificity | SIN3A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ChIP assay: 1-3 µL, Immunocytochemistry: 1:50-1:500, Immunofluorescence: 1:50-1:500, Immunohistochemistry (Paraffin): 1:50-1:500, Immunoprecipitation: Assay dependent, Western Blot: 0.5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SIN3A Polyclonal Antibody. Mammalian Sin3 (mSin3) is a 150 kDa protein closely related to the yeast SIN3 repressor protein involved in the transcriptional repression of many genes. There are two mammalian isoforms, mSin3A and mSin3B. Containing 4 paired amphipathic helix domains (PAH domains), mSin3A and mSin3B have been shown to directly interact with several other transcriptional repressor proteins including HDAC1, HDAC2, RbAp46, the methyl CpG binding protein MeCP2, the Mad/Max heterodimer, and the corepressors silencing mediator of retinoic acid & thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR). |
Immunogen | n/a |
Other Names | Mammalian Sin3A, SIN |
Gene, Accession # | Entrez: 20466, 25942; Uniprot: Q60520, Q96ST3 |
Catalog # | PA1-870 |
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Order / More Info | SIN3A Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 20935208, 23280436, 23612983, 24234443, 28394263 |
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