产品详情 |
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Antigenic Specificity | CD11b |
Clone | C67F154 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD11b Monoclonal Antibody (C67F154), eBioscience™. CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18). The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3). CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions. CD11b is expressed on 8% of sp |
Immunogen | n/a |
Other Names | CD11 antigen-like family member B; CD11B; CD11B (p170); cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component receptor 3 alpha-a; complement receptor type 3; CR-3 alpha chain; CR3A; Integrin alpha M; integrin alpha-M; leukocyte adhesion receptor MO1; MAC-1; Mac-1 alpha; MAC1A; macrophage antigen alpha; MGC117044; MO1A; SLEB6 |
Gene, Accession # | Entrez: 3684; Uniprot: P11215 |
Catalog # | 14-0196-82 |
Price | |
Order / More Info | CD11b Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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