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Antigenic Specificity | CD11b |
Clone | ICRF44 |
Host Species | Mouse |
Reactive Species | baboon, chimpanzee, cynomolgus monkey, human, rhesus monkey |
Isotype | IgG1, kappa |
Format | allophycocyanin (APC) conjugate |
Size | 25 Tests |
Concentration | n/a |
Applications | Flow Cytometry: 5 µL (0.5 µg)/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD11b Monoclonal Antibody (ICRF44), APC, eBioscience™. CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18). The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3). CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions. CD11b is expressed on 8% o |
Immunogen | n/a |
Other Names | CD11B, CR3A, MAC-1, MAC1A, MGC117044, MO1A, SLEB6, Integrin alpha M |
Gene, Accession # | Entrez: 101866035, 3684, 454069, 714832; Uniprot: P11215 |
Catalog # | 17-0118-41 |
Price | |
Order / More Info | CD11b Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 20308313, 21059848, 22153812, 24610880, 25030167, 25193428, 25266422, 25484051, 25986473, 26176858, 26372309, 27460500, 27530414, 28903338, 29115434, 29190915, 29275859, 29482598 |
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