| 产品详情 |
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| Antigenic Specificity | BRMS1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BRMS1 Polyclonal Antibody. Breast cancer metastasis-suppressor 1 (BRMS1) acts as a mediator of metastasis suppression in several types of cancer including ovarian, lung, bladder, and murine mammary. BRMS1 mRNA is expressed in various tissues, including ovary, prostate, testis, and colon, but the protein is primarily detected in term placenta. BRMS1 suppresses metastasis without inhibiting tumorigenicity by modifying several metastasis-associated phenotypes. BRMS1 may participate in transcriptional regulation by binding to the mSin3/histone deacetylase complex. The expression of BRMS1 in certain cells increases connexin Cx43 expression and reduces connexin Cx32 expression. This produces a gap junction that increases intercellular communicati |
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| Immunogen | n/a |
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| Other Names | Breast cancer metastasis-suppressor 1; BRMS1; BRMS 1 |
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| Gene, Accession # | Entrez: 107392, 25855, 293668; Uniprot: Q5M7T3, Q99N20, Q9HCU9 |
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| Catalog # | PA5-75260 |
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| Price | |
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| Order / More Info | BRMS1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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