产品详情 |
Edit |   |
Antigenic Specificity | LGMN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, canine, equine, guinea pig, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | LGMN Polyclonal Antibody. This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been descri |
Immunogen | n/a |
Other Names | legumain, AEP, LGMN1, PRSC1 |
Gene, Accession # | Entrez: 100053265, 100346565, 100718170, 19141, 281281, 406625, 480232, 5641, 63865; Uniprot: O89017, Q95M12, Q99538, Q9R0J8 |
Catalog # | PA5-45866 |
Price | |
Order / More Info | LGMN Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
|
|