| 产品详情 |
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| Antigenic Specificity | LGP2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LGP2 Polyclonal Antibody. Anti-viral innate immune responses are triggered by pathogen-associated molecular patters (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms. The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids. Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm. A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regula |
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| Immunogen | n/a |
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| Other Names | D11LGP2, D11lgp2e, LGP2; RIG-I-like receptor LGP2; RLR; RNA helicase LGP2; ortholog of mouse D11lgp2; probable ATP-dependent RNA helicase DHX58; probable ATP-dependent helicase LGP2; protein D11Lgp2 homolog |
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| Gene, Accession # | Entrez: 303538, 79132, 80861; Uniprot: Q96C10, Q99J87 |
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| Catalog # | PA5-20435 |
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| Price | |
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| Order / More Info | LGP2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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