产品详情 |
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Antigenic Specificity | DHH |
Clone | 2G5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, kappa |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: Assay-Dependent, Western Blot: 1-5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DHH Monoclonal Antibody (2G5). This gene encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifas |
Immunogen | n/a |
Other Names | GDXYM, HHG-3, SRXY7, desert hedgehog homolog, desert hedgehog protein, mutant desert hedgehog |
Gene, Accession # | Entrez: 50846; Uniprot: O43323 |
Catalog # | MA5-21835 |
Price | |
Order / More Info | DHH Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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