| 产品详情 |
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| Antigenic Specificity | Bi-1 |
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| Clone | 20F430 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG2b, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 5-10 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Bi-1 Monoclonal Antibody (20F430). BI-1 (Bax Inhibitor 1) is in anti-apoptotic protein that has been linked to protection from apoptosis induced endoplasmic reticulum (ER) stress (reviewed in Bailley-Maitre et al, 2007). BI-1 contains several transmembrane domains, localizes to ER membranes, and has cytoprotective functions that are conserved in both animals and plants. BI-1 suppresses apoptosis induced by ectopic expression of the proapoptotic protein Bax as well as other types of stimuli. Cells from BI-1 knockout (KO) mice are hypersensitivite to apoptosis induced by ER stress-causing chemical agents (thapsigargin, tunicamycin, and brefeldin A) or by ischemia-reperfusion (IR) injury. Conversely, overexpression of BI-1 protects against apo |
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| Immunogen | n/a |
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| Other Names | BAXI1, BI-1, TEGT |
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| Gene, Accession # | Entrez: 110213, 24822, 7009; Uniprot: P55061, P55062, Q9D2C7 |
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| Catalog # | MA1-41108 |
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| Price | |
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| Order / More Info | Bi-1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 26676227 |
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| 产品资料 |
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