| 产品详情 |
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| Antigenic Specificity | BICD1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 2.5 µg/mL, Immunofluorescence: 10 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BICD1 Polyclonal Antibody. BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport. BICD1 will also interact with Rab6B, a Rab6 isoform that is expressed primarily in brain. Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating that BICD1 is involved in the Rab6B regulation of retrograde cargo transport in neuronal cells. |
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| Immunogen | n/a |
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| Other Names | BICD; bic-D 1; cytoskeleton-like bicaudal D protein homolog 1; protein bicaudal D homolog 1 |
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| Gene, Accession # | Entrez: 12121, 362466, 636; Uniprot: Q8BR07, Q96G01 |
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| Catalog # | PA5-20555 |
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| Price | |
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| Order / More Info | BICD1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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