| 产品详情 |
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| Antigenic Specificity | BICD2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-10 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BICD2 Polyclonal Antibody. BICD2 is the second human homolog discovered to the Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. Similar to the highly homologous protein BICD1, BICD2 can bind to dynein-dynactin complex, primarily through the dynamitin subunit of dynactin. The C-terminus of BICD2 targets the protein to the Golgi complex while the N-terminal domain of BICD2 co-immunoprecipitates with cytoplasmic dynein, suggesting BICD2 plays a role in the dynein-dynactin interaction on the surface of membranous organelles. Mice engineered to overexpress the BICD2 amino terminal domain in neurons developed amyotrophic lateral s |
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| Immunogen | n/a |
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| Other Names | Protein bicaudal D homolog 2; Bic-D 2; BICD2; KIAA0699 |
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| Gene, Accession # | Entrez: 23299; Uniprot: Q8TD16 |
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| Catalog # | A303-318A |
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| Price | |
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| Order / More Info | BICD2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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