| 产品详情 |
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| Antigenic Specificity | BID |
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| Clone | 21F10 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a, kappa |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Immunoprecipitation: 2 µg, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BID Monoclonal Antibody (21F10). BID is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. Bid is a member of the BCL-2 family of cell death regulators. BID is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. BID is also a pro-apoptotic member of the Bcl 2 family. BID usually exists in an inactive form in the cytosolic fraction of living cells and becomes cleaved and activated by caspase 8 in response to TNF alpha or Fas ligand. Once BID is cleaved, the C-terminal 15 kDa fragment of BID (p15) translocates onto mitochondria and is sufficient to trigger cytochrome c r |
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| Immunogen | n/a |
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| Other Names | FP497, MGC15319, MGC42355 |
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| Gene, Accession # | Entrez: 637; Uniprot: P55957 |
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| Catalog # | LF-MA0208 |
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| Price | |
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| Order / More Info | BID Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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