产品详情 |
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Antigenic Specificity | Bif1 |
Clone | 30A882.1.1 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, Kappa |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: Assay-Dependent, Immunofluorescence: Assay-Dependent, Immunohistochemistry: 5 µg/mL, Immunoprecipitation: 1:10-1:500, Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bif1 Monoclonal Antibody (30A882.1.1). The Bcl-2 family consists of anti-apoptotic (or cell survival) genes, such as Bcl-2, Bcl-XL and pro-apoptotic (or cell death) genes including Bax and BAD. In addition to its anti-apoptotic effect, Bcl-2 also inhibits progression through the cell cycle. Functional interactions between family members as well as binding to other cellular proteins modulate their activities. Bcl-2 family members are important in normal tissue development, homeostasis, and disease states. Bcl-2 prevents cell death by forming heterodimers with Bax and Bad (1). Bax promotes cell death by forming homodimers, which can be blocked by forming heterodimers with Bcl-2 or BCL-XL. Recently, using yeast two-hybrid system Cuddeback et a |
Immunogen | n/a |
Other Names | CGI-61, Bif-1, PPP1R70, dJ612B15.2, Bax-interacting factor 1, SH3 domain-containing GRB2-like protein B1, SH3-containing protein SH3GLB1, endophilin-B1, protein phosphatase 1, regulatory subunit 70 |
Gene, Accession # | Entrez: 51100, 54673; Uniprot: Q9JK48, Q9Y371 |
Catalog # | MA5-16170 |
Price | |
Order / More Info | Bif1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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