产品详情 |
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Antigenic Specificity | CD46 |
Clone | MEM-258 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 200 µg |
Concentration | n/a |
Applications | Flow Cytometry: 1:10-1:50, Functional Assay: Assay Dependent, Immunofluorescence: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD46 Monoclonal Antibody (MEM-258). The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system. At least fourte |
Immunogen | n/a |
Other Names | AHUS2, MCP, MGC26544, MIC10, TLX, TRA2.10 |
Gene, Accession # | Entrez: 4179; Uniprot: P15529 |
Catalog # | MA1-82140 |
Price | |
Order / More Info | CD46 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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