| 产品详情 |
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| Antigenic Specificity | CD47 |
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| Clone | B6H12.2 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5 µg/test, Immunofluorescence: Assay Dependent, Immunoprecipitation: 2 µg/mL, Western Blot: 1:10-1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD47 Monoclonal Antibody (B6H12.2). CD47 (integrin-associated protein, IAP) is a ubiquitously expressed cell surface transmembrane glycoprotein interacting with several integrins and regulating their functions. Engagement of CD47 by soluble ligands or counter receptors modulates various signaling pathways, such as activation of heterotrimeric G proteins. Functionally, CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. CD47 is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. CD47 has broad tissue distribution, is reduced in expression on Rh erythrocytes. CD47 acts as a lig |
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| Immunogen | n/a |
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| Other Names | IAP, MER6, OA3, CD47 antigen, CD47 glycoprotein, Rh-related antigen, leukocyte surface antigen CD47 |
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| Gene, Accession # | Entrez: 961; Uniprot: Q08722 |
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| Catalog # | MA5-11895 |
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| Price | |
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| Order / More Info | CD47 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12947004, 15498560, 16225657, 18392110, 23866045 |
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