产品详情 |
Edit |   |
Antigenic Specificity | MSC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50-1:200 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MSC Polyclonal Antibody. MyoD-E or musculin-E heterodimers bind avidly to consensus E box motifs, which are functionally important elements in the promoter regions of many musclespecific terminal differentiation genes. MyoD complexes potently induce transcriptional activation, while musculin complexes bind adjacent to MyoD DNA-binding regions to represses MyoD activity, which then results in the delayed expression of muscle-specific genes. Musculin is highly expressed in undifferentiated and proliferating myoblasts in culture, and its expression is down regulated during myogenesis and at the onset of terminal differentiation. |
Immunogen | n/a |
Other Names | Musculin; Activated B-cell factor 1; ABF-1; Class A basic helix-loop-helix protein 22; bHLHa22; MSC; ABF1; BHLHA22 |
Gene, Accession # | Entrez: 17681, 312897, 9242; Uniprot: O60682, O88940 |
Catalog # | PA5-75216 |
Price | |
Order / More Info | MSC Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
|
|