| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | MSH2 |
|---|
| Clone | FE11 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, mouse |
|---|
| Isotype | IgG1, kappa |
|---|
| Format | purified |
|---|
| Size | 50 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 2 µg/mL |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | MSH2 Monoclonal Antibody (FE11). MSH2 is involved in DNA repair as a mismatch repair protein, and mutations of MSH2 are found in approximately 50% of inherited non polyposis colorectal carcinoma (HNPCC) (Lynch syndrome) cases. HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. |
|---|
| Immunogen | n/a |
|---|
| Other Names | COCA1, FCC1, HNPCC, HNPCC1, LCFS2, DNA mismatch repair protein Msh2, hMSH2 |
|---|
| Gene, Accession # | Entrez: 17685, 4436; Uniprot: P43246, P43247 |
|---|
| Catalog # | 33-7900 |
|---|
| Price | |
|---|
| Order / More Info | MSH2 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 14760069, 15509520, 15510606, 15704157, 15930362, 15958853, 16136384, 16803513, 16810312, 17943475, 17973265, 18202787, 18254781, 18949393, 19124477, 19275958, 19464205, 19567531, 19821155, 20227038, 21733559, 21937259, 22740444, 23066952, 23155266, 23194196, 23797051, 24205245, 24315830, 24432405, 24592941, 25710585, 25798424, 26714314, 26964739, 27816197 |
|---|
| 产品资料 |
|
|