| 产品详情 |
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| Antigenic Specificity | MSH6 |
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| Clone | 5B11 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1/500 - 1/2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MSH6 Monoclonal Antibody (5B11). This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. |
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| Immunogen | n/a |
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| Other Names | GTBP, HNPCC5, HSAP, DNA mismatch repair protein Msh6; G/T mismatch-binding protein; GTMBP; hMSH6; mutS-alpha 160 kDa subunit; p160; sperm-associated protein |
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| Gene, Accession # | Entrez: 2956; Uniprot: P52701 |
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| Catalog # | MA5-15917 |
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| Price | |
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| Order / More Info | MSH6 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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