| 产品详情 |
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| Antigenic Specificity | p400 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | p400 Polyclonal Antibody. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity. |
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| Immunogen | n/a |
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| Other Names | CAGH32, P400, TNRC12, CAG repeat protein 32, E1A-binding protein p400, domino homolog, hDomino, p400 SWI2/SNF2-related protein, p400 kDa SWI2/SNF2-related protein, trinucleotide repeat containing 12, trinucleotide repeat-containing gene 12 protein |
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| Gene, Accession # | Entrez: 57634; Uniprot: Q96L91 |
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| Catalog # | PA5-30780 |
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| Price | |
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| Order / More Info | p400 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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