| 产品详情 |
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| Antigenic Specificity | p53 |
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| Clone | BP53-12 |
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| Host Species | Mouse |
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| Reactive Species | human, nonhuman primate |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Immunocytochemistry: Assay Dependent, Immunohistochemistry (Paraffin): Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | p53 Monoclonal Antibody (BP53-12). The tumor suppressor protein, p53, is a sequence specific transcription factor that is activated by cellular stress. p53 mediates cell cycle arrest or apoptosis in response to DNA damage or starvation for pyrimidine nucleotides. p53 is up-regulated in response to stress signals and stimulated to activate transcription of specific genes, resulting in expression of p21waf1 and other proteins involved in G1 or G2/M arrest. The structure of p53 comprises an N-terminal transactivation domain, a central DNA-binding domain, an oligomerisation domain, and a C-terminal regulatory domain. There are various phosphorylation sites on p53, of which the phosphorylation at Ser15 is important for p53 activation and stabili |
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| Immunogen | n/a |
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| Other Names | antigen NY-CO-13, cellular tumor antigen p53, p53 tumor suppressor, phosphoprotein p53, transformation-related protein 53, TP53 |
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| Gene, Accession # | Entrez: 7157; Uniprot: P04637 |
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| Catalog # | MA1-19055 |
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| Price | |
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| Order / More Info | p53 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10218673, 10408175, 10464290, 10547465, 10632346, 10638593, 10648628, 11320032, 11445851, 11511786, 11782364, 12077343, 12483005, 12522004, 12588418, 12682632, 12765416, 12902986, 12919956, 14506735, 14629754, 14738320, 14997499, 15196999, 15229249, 15260851, 15260857, 15268709, 15381086, 15467455, 15489653, 15558705, 15607904, 15657348, 15663677, 16198399, 16360120, 16614520, 16632118, 16700663, 16803476, 16810069, 16824077, 17408702, 17413990, 17457759, 17581415, 17870432, 18067636, 18245538, 18388863, 18608579, 19041683, 19189638, 19527492, 19949897, 20006376, 20122174, 20427035, 20712650, 20714943, 20719821, 20805583, 20881860, 20963646, 21060032, 21062935, 21072900, 21937381, 21951670, 21997193, 22009819, 22103332, 22109999, 22121263, 22242180, 22306610, 22365624, 22589537, 22609107, 22615883, 22693253, 22975381, 23178935, 23310950, 23319821, 23324739, 23372829, 23410662, 23465288, 23469219, 23526092, 23625597, 23702729, 23714252, 23739040, 23826420, 23899963, 23969757, 24001413, 24117486, 24179525, 24309326, 24556061, 24674866, 24722987, 24941295, 26241661, 27030265, 27935156, 7736384, 7745116, 9699889 |
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