| 产品详情 |
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| Antigenic Specificity | p53 |
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| Clone | BP53-12 |
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| Host Species | Mouse |
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| Reactive Species | human, nonhuman primate |
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| Isotype | IgG2a |
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| Format | fluorescein (FITC) conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay dependent, Immunofluorescence: Assay dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | p53 Monoclonal Antibody (BP53-12), FITC. The tumor suppressor protein, p53, is a sequence specific transcription factor that is activated by cellular stress. p53 mediates cell cycle arrest or apoptosis in response to DNA damage or starvation for pyrimidine nucleotides. p53 is up-regulated in response to stress signals and stimulated to activate transcription of specific genes, resulting in expression of p21waf1 and other proteins involved in G1 or G2/M arrest. The structure of p53 comprises an N-terminal transactivation domain, a central DNA-binding domain, an oligomerisation domain, and a C-terminal regulatory domain. There are various phosphorylation sites on p53, of which the phosphorylation at Ser15 is important for p53 activation and s |
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| Immunogen | n/a |
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| Other Names | antigen NY-CO-13, cellular tumor antigen p53, p53 tumor suppressor, phosphoprotein p53, transformation-related protein 53, TP53 |
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| Gene, Accession # | Entrez: 7157; Uniprot: P04637 |
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| Catalog # | MA1-19551 |
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| Price | |
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| Order / More Info | p53 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10408175, 10464290, 11782364, 12167105, 12522004, 12682632, 12765416, 12919956, 14506735, 14738320, 14997499, 15196999, 15229249, 15260857, 15381086, 15467455, 15489653, 15657348, 16084457, 16614520, 16824077, 17408702, 17413990, 17457759, 17581415, 18245538, 18388863, 18608579, 19189638, 19527492, 20063202, 20122174, 20427035, 20881860, 20963646, 21060032, 21062935, 21937381, 21997193, 22103332, 22109999, 22121263, 22242180, 22365624, 22589537, 22609107, 22615883, 22693253, 22975381, 23178935, 23310950, 23319821, 23372829, 23410662, 23469219, 23526092, 23702729, 23714252, 23739040, 24001413, 24117486, 24179525, 24309326, 24556061, 24674866, 24722987 |
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