| 产品详情 |
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| Antigenic Specificity | p53 |
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| Clone | DO-7 |
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| Host Species | Mouse |
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| Reactive Species | bovine, human, nonhuman primate |
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| Isotype | IgG2b, kappa |
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| Format | biotin conjugate |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5 µg/test, Immunocytochemistry: 1:20-1:200, Immunofluorescence: 1:20-1:200, Immunohistochemistry (Paraffin): 1:100-1:200, Immunoprecipitation: 1:50-1:100, Western Blot: 1:50-1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | p53 Monoclonal Antibody (DO-7), Biotin. The tumor suppressor protein, p53, is a sequence specific transcription factor that is activated by cellular stress. p53 mediates cell cycle arrest or apoptosis in response to DNA damage or starvation for pyrimidine nucleotides. p53 is up-regulated in response to stress signals and stimulated to activate transcription of specific genes, resulting in expression of p21waf1 and other proteins involved in G1 or G2/M arrest. The structure of p53 comprises an N-terminal transactivation domain, a central DNA-binding domain, an oligomerisation domain, and a C-terminal regulatory domain. There are various phosphorylation sites on p53, of which the phosphorylation at Ser15 is important for p53 activation and st |
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| Immunogen | n/a |
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| Other Names | antigen NY-CO-13, cellular tumor antigen p53, p53 tumor suppressor, phosphoprotein p53, transformation-related protein 53, TP53 |
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| Gene, Accession # | Entrez: 281542, 7157; Uniprot: P04637, P67939 |
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| Catalog # | MA5-12554 |
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| Price | |
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| Order / More Info | p53 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10940505, 11782364, 12167105, 12522004, 12682632, 12765416, 12834749, 13679208, 14506735, 14633602, 14738320, 14997499, 14999779, 15140542, 15188025, 15196999, 15229249, 15260857, 15467455, 15468998, 15489653, 15657348, 15719276, 15806378, 15817070, 15992918, 16080465, 16084457, 16187230, 16413663, 16439685, 16614520, 16688362, 16787530, 16804906, 16810543, 16824077, 17295649, 17352244, 17397945, 17413990, 17457759, 17483435, 17581415, 17624738, 17641794, 17722244, 17724798, 17882495, 17947469, 18245538, 18342452, 18388863, 18608579, 18688713, 18758635, 18758639, 18990760, 19034659, 19035275, 19189638, 19202066, 19293613, 19434317, 19525400, 19527492, 19577853, 19687096, 19735876, 19815839, 19846940, 20052735, 20108544, 20122174, 20214740, 20349288, 20427035, 20656324, 20881860, 20944119, 20952295, 20963646, 21053097, 21060032, 21062935, 21153652, 21469425, 21937381, 22103332, 22107367, 22109999, 22121263, 22192803, 22249577, 22384045, 22589537, 22609107, 22615883, 22634494, 22693253, 22716306, 22975381, 23178935, 23310950, 23319821, 23372829, 23410662, 23469219, 23526092, 23702729, 23714252, 23739040, 24001413, 24117486, 24179525, 24309326, 24556061, 24674866, 24722987 |
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