产品详情 |
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Antigenic Specificity | ADAM10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 10 µg/mL, Western Blot: 1:1000-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ADAM10 Polyclonal Antibody. Proinflammatory cytokine tumor necrosis factor-alpha (TNF-a) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-a, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-a, notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned and desig |
Immunogen | n/a |
Other Names | AD10, HsT18717, MADM, kuz, CDw156 |
Gene, Accession # | Entrez: 102; Uniprot: O14672 |
Catalog # | PA5-19898 |
Price | |
Order / More Info | ADAM10 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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