产品详情 |
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Antigenic Specificity | ADAM17 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 50 µg |
Concentration | n/a |
Applications | peptide-ELISA: 1:32,000, Western Blot: Assay dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ADAM17 Polyclonal Antibody. TNF alpha is a pro-inflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. It is synthesized as a 26K type II membrane-bound precursor that is cleaved by aconvertase to generate secreted 17K mature TNF alpha. TNF alpha converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately. TACE is a membrane-bound metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease). TACE also processes other cell surface proteins, including TNF receptor, TGF alpha, the L-selectin adhesion molecule, and alpha-cleavage of amyloid protein precursor (APP). TACE mRNA is exp |
Immunogen | n/a |
Other Names | A disintegrin and metalloproteinase domain 17, TNF-alpha-converting enzyme, TNF-alpha convertase, Snake venom-like protease, CD156b antigen, CSVP, TACE |
Gene, Accession # | Entrez: 11491, 57027, 6868; Uniprot: P78536, Q9Z0F8, Q9Z1K9 |
Catalog # | PA1-31074 |
Price | |
Order / More Info | ADAM17 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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