| 产品详情 |
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| Antigenic Specificity | ADAMTS4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): Assay dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ADAMTS4 Polyclonal Antibody. ADAMTS4, also known as aggrecanase-1, is a Metallopeptidase M12B type protease that is responsible for degradation of the articular cartilage protein aggrecan and the brain extracellular matrix proteoglycan brevican. The ADAMTS4 protein contains a signal sequence, a propeptide domain, a catalytic domain, a disintegrin-like motif, and a C-terminal domain with a thrombospondin (TSP) type 1 motif. ADAMTS4 has been implicated in inflammatory joint diseases, and it also may be a factor in the progression of glioma and Alzheimer's disease. ADAMTS4 expression has been documented in normal human brain, cartilage, heart, lung, placenta, muscle, and synovium. ESTs have been isolated from human tissue libraries, including |
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| Immunogen | n/a |
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| Other Names | Aggrecanase 1, A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAM-TS 4, ADAM-TS4, ADMP-1 |
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| Gene, Accession # | Entrez: 9507; Uniprot: O75173 |
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| Catalog # | PA1-33177 |
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| Price | |
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| Order / More Info | ADAMTS4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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