| 产品详情 |
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| Antigenic Specificity | ALDH18A1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:20-1:50, Western Blot: 0.4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ALDH18A1 Polyclonal Antibody. This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene. |
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| Immunogen | n/a |
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| Other Names | ALDH18A1; aldehyde dehydrogenase 18 family, member A1; GSAS; MGC117316; P5CS; PYCS; aldehyde dehydrogenase 18A1; delta1-pyrroline-5-carboxlate synthetase; pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase) |
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| Gene, Accession # | Entrez: 361755, 56454, 5832; Uniprot: P54886, Q9Z110 |
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| Catalog # | PA5-52546 |
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| Price | |
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| Order / More Info | ALDH18A1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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