产品详情 |
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Antigenic Specificity | Quinidine |
Clone | QD13-406.6.1 |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | purified |
Size | 500 µg |
Concentration | n/a |
Applications | ELISA: 1-10 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Quinidine Monoclonal Antibody (QD13-406.6.1). Quinidine is an alkaloid extracted from the bark of the Cinchona tree with class 1A antiarrhythmic and antimalarial effects. Quinidine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the sodium influx required for the initiation and conduction of impulses resulting in an increase of the threshold for excitation and decreased depolarization during phase 0 of the action potential. In addition, the effective refractory period (ERP), action potential duration (APD), and ERP/APD ratios are increased, resulting in decreased conduction velocity of nerve impulses. Quinidine exerts its antimalarial activity by acting primarily as an intra-er |
Immunogen | n/a |
Other Names | (+)-Quinidine; Chinidin; Pitayine; Quinidex; Cin-Quin; C20H24N2O2 |
Gene, Accession # | n/a |
Catalog # | MA1-10749 |
Price | |
Order / More Info | Quinidine Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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