产品名称 c-Abl Antibody from INVITROGEN ANTIBODIES
产品货号 PA5-12538
产品价格 现货询价,电话:010-67529703
产品规格 400 µL
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic Specificityc-Abl
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size400 µL
Concentrationn/a
ApplicationsWestern Blot: 1:1000
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Descriptionc-Abl Polyclonal Antibody. c-Abl (Abelson murine leukemia viral oncogene homolog 1, ABL1) is a 140 kDa proto-oncogene member of the Src family of non-receptor tyrosine kinases. c-Abl has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns c-Abl into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR and c-Abl genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for c-Abl. In chronic myelog
Immunogenn/a
Other Namesn/a
Gene, Accession #Entrez: 25; Uniprot: P00519
Catalog #PA5-12538
Price
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Product Specific Referencesn/a
产品资料