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Antigenic Specificity | CACNA2D1 |
Clone | 20A |
Host Species | Mouse |
Reactive Species | guinea pig, human, mouse, rabbit, rat |
Isotype | IgG2a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Flow Cytometry: 1:100-1:200, Immunocytochemistry: 1:250, Immunofluorescence: Assay dependent, Immunohistochemistry (Frozen): 1:500, Immunohistochemistry (Paraffin): 1:500, Western Blot: 1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CACNA2D1 Monoclonal Antibody (20A). Voltage-sensitive calcium channels mediate the entry of calcium into many types of excitable cells and thus play a key role in neurotransmitter release and excitation-contraction (E-C) coupling. The 1,4-dihydropyridines (DHPs) are synthetic organic compounds which can be used to identify the L-type calcium channels that are found in all types of vertebrate muscle, neuronal and neuroendocrine cells. The DHP receptor is part of the L-type calcium channel complex and is thought to be the voltage sensor in E-C coupling. The purified DHP receptor isolated from triads is composed of at least four subunits. The alpha-1 subunit contains the binding site for the DHPs and shows high sequence homology to the voltage |
Immunogen | n/a |
Other Names | DHP, Calcium Channel |
Gene, Accession # | Entrez: 100009105, 100728887, 12293, 25399, 781; Uniprot: O08532, P13806, P54289, P54290 |
Catalog # | MA3-921 |
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Order / More Info | CACNA2D1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 10555569, 10825439, 11133930, 11289313, 11306709, 11718668, 11796649, 12739153, 12777394, 12800977, 12946355, 12959958, 14670813, 15471972, 16483859, 16938495, 17574269, 17596281, 18645228, 19201998, 20008467, 20060001, 20407082, 20595538, 21056571, 21209095, 21262876, 21310482, 22180652, 24278453, 25384984, 26403541, 27129199, 27641745, 28096168, 9472035 |
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