| 产品详情 |
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| Antigenic Specificity | CRX |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CRX Polyclonal Antibody. The cone-rod homeobox-containing gene (CRX) encodes a transcription factor that coordinates the expression of several photoreceptor genes in the developing retina, including opsin and rhodopsin. Specifically, CRX binds the OTX motif (TAATCC/A) upstream from photoreceptor genes. The CRX gene is also expressed in the pinealocytes of the pineal gland and may regulate pineal circadian activity by controling the expression of melatonin synthesis genes. Furthermore, CRX(-) mice exhibit disruption of circadian rhythms. The human CRX gene maps to chromosome 19q13.3 within the region of the cone-rod dystrophy-2 locus (CORD2). Mutations in the CRX gene are implicated in the visual pathologies of CORD, Leber congenital amauros |
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| Immunogen | n/a |
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| Other Names | Cone rod homeobox; Cone rod homeobox protein; Cone-rod homeobox protein; CORD 2; CRD; CRX; CRX_HUMAN; LCA 7; LCA7; Orthodenticle homeobox 3; OTX 3; OTX3; |
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| Gene, Accession # | Entrez: 12951, 1406, 60446; Uniprot: O43186, O54751 |
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| Catalog # | PA5-76805 |
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| Price | |
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| Order / More Info | CRX Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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