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| Antigenic Specificity | CRY1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CRY1 Polyclonal Antibody. Various biochemical, physiological and behavioural processes display circadian rhythms controlled by an internal biological clock. The central gears driving this clock appear to be composed of an autoregulatory transcription/posttranslation-based feedback loop. Cryptochrome 1 (CRY1) and 2 (CRY2) are DNA-binding flavoproteins that bear some homology to blue-light receptors and photolyases. In Drosophila, CRY is a photoreceptor for the circadian clock where it binds to the clock component TIM in a light-dependent fashion and blocks its function. Mammalian CRY1 and CRY2 function via light-independent interactions with circadian genes CLOCK and BMAL1, as well as with PER1, PER2, and TIM. They seem to act as light-i |
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| Immunogen | n/a |
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| Other Names | Cryptochrome-1; PHLL1 |
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| Gene, Accession # | Entrez: 1407; Uniprot: Q16526 |
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| Catalog # | PA5-13124 |
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| Price | |
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| Order / More Info | CRY1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 28186121 |
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