| 产品详情 |
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| Antigenic Specificity | LIMK1 |
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| Clone | OTI6B4 |
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| Host Species | Mouse |
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| Reactive Species | canine, human, mouse, nonhuman primate, rat |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:100, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LIMK1 Monoclonal Antibody (OTI6B4). LIMK1, a member of the Ser/Thr protein kinase family, may be a component of an intracellular signaling pathway and may be involved in brain development. It phosphorylates and inactivates the actin binding/depolymerizing factor cofilin and induces actin cytoskeletal changes. The LIM domain interacts with the cytoplasmic domain of NRG1, and this cytoplasmic protein also binds ROCK1, whic phosphorylates LIMK1 on serine and/or threonine residues. Highest expression occurs in both adult and fetal nervous systems. It is detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex, and is expressed to a lesser extent in heart and skeletal muscle. Haploinsuffic |
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| Immunogen | n/a |
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| Other Names | LIM domain kinase 1, LIMK-1 |
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| Gene, Accession # | Entrez: 16885, 3984, 489800, 65172, 699494; Uniprot: P53667, P53668, P53669 |
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| Catalog # | MA5-25569 |
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| Price | |
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| Order / More Info | LIMK1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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