产品详情 |
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Antigenic Specificity | Cyclin B1 |
Clone | 5G6 |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG1 |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Flow Cytometry: 1/200 - 1/400, Immunocytochemistry: 1:200-1:1000, Immunofluorescence: 1/200 - 1/1000, Western Blot: 1/500 - 1/2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cyclin B1 Monoclonal Antibody (5G6). Cyclins bind to and regulate the activity of the Cyclin dependent protein kinases (CDKs). Cyclin B1 or CCNB1 is a regulatory protein involved in mitosis. It is essential for the control of the cell cycle at the G2/M transition. Cyclin B1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. Cyclin B1 is not ubiquitinated during G2/M phase, resulting in its steady accumulation during G2 phase, followed by abrupt APC dependent destruction at the end of mitosis. Destruction of Cyclin B1 is required for cell cycle progr |
Immunogen | n/a |
Other Names | CCNB; CCNB1 |
Gene, Accession # | Entrez: 25203, 891; Uniprot: P14635, P30277 |
Catalog # | MA5-15714 |
Price | |
Order / More Info | Cyclin B1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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