| 产品详情 |
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| Antigenic Specificity | Cyclin B1 |
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| Clone | GNS11 |
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| Host Species | Mouse |
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| Reactive Species | hamster, human, mouse, rat |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:10-1:200, Immunofluorescence: 1:10-1:200, Immunohistochemistry (Paraffin): 2-4 µg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 1:100-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cyclin B1 Monoclonal Antibody (GNS11). Cyclins bind to and regulate the activity of the Cyclin dependent protein kinases (CDKs). Cyclin B1 or CCNB1 is a regulatory protein involved in mitosis. It is essential for the control of the cell cycle at the G2/M transition. Cyclin B1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. Cyclin B1 is not ubiquitinated during G2/M phase, resulting in its steady accumulation during G2 phase, followed by abrupt APC dependent destruction at the end of mitosis. Destruction of Cyclin B1 is required for cell cycle pro |
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| Immunogen | n/a |
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| Other Names | G2/mitotic-specific cyclin B1, G2/mitotic-specific cyclin-B1,OTTHUMP00000223023 |
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| Gene, Accession # | Entrez: 100770842, 25203, 268697, 891; Uniprot: P14635, P24860, P30277 |
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| Catalog # | MA5-14327 |
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| Price | |
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| Order / More Info | Cyclin B1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12472774, 15767402, 17449943, 21264543, 22837015, 23165652, 26270673, 27525972, 27548200 |
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