| 产品详情 |
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| Antigenic Specificity | Cyclin B1 |
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| Clone | V152 |
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| Host Species | Mouse |
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| Reactive Species | hamster, human, mouse, nonhuman primate, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay Dependent, Immunocytochemistry: 1:50-1:500, Immunofluorescence: 1:50-1:500, Immunohistochemistry (Paraffin): 1:10 - 1:2000, Immunoprecipitation: 1 µg, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cyclin B1 Monoclonal Antibody (V152). Cyclins bind to and regulate the activity of the Cyclin dependent protein kinases (CDKs). Cyclin B1 or CCNB1 is a regulatory protein involved in mitosis. It is essential for the control of the cell cycle at the G2/M transition. Cyclin B1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. Cyclin B1 is not ubiquitinated during G2/M phase, resulting in its steady accumulation during G2 phase, followed by abrupt APC dependent destruction at the end of mitosis. Destruction of Cyclin B1 is required for cell cycle prog |
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| Immunogen | n/a |
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| Other Names | CCNB1, CCNB, G2/Mitotic-Specific Cyclin B1, cyclin B1 |
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| Gene, Accession # | Entrez: 100770842, 25203, 268697, 891; Uniprot: P14635, P24860, P30277 |
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| Catalog # | MA1-155 |
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| Price | |
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| Order / More Info | Cyclin B1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 24983972, 26700735 |
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