产品详情 |
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Antigenic Specificity | Bestrophin 1 |
Clone | E6-6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: Assay-Dependent, Immunofluorescence: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Immunoprecipitation: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bestrophin 1 Monoclonal Antibody (E6-6). Best macular dystrophy (BMD) or vitelliform macular dystrophy (VMD2), is an autosomal form of macular degeneration, characterized by a depressed light peak in the electrooculogram (EOG). It is inherited and has an early onset. Bestrophin is a 68 kDa basolateral plasma membrane protein encoded by the VMD2 gene. Bestrophins function is still unknown, but data suggests that it is a chloride channel that plays a role in generating the altered EOG in Best disease patients. In addition, Bestrophin is a useful biochemical and histological marker of RPE (retinal pigment epithelial cells) cells. |
Immunogen | n/a |
Other Names | ARB, BEST, BMD, RP50, TU15B, VMD2 |
Gene, Accession # | Entrez: 7439; Uniprot: O76090 |
Catalog # | MA1-16739 |
Price | |
Order / More Info | Bestrophin 1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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