产品详情 |
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Antigenic Specificity | Bestrophin 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | lyophilized |
Applications | Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 0.5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bestrophin 1 Polyclonal Antibody. This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Al |
Immunogen | n/a |
Other Names | Bestrophin-1, TU15B, Vitelliform macular dystrophy protein 2, BEST1, VMD2 |
Gene, Accession # | Entrez: 7439; Uniprot: O76090 |
Catalog # | PA5-78867 |
Price | |
Order / More Info | Bestrophin 1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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