产品详情 |
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Antigenic Specificity | CYP1A2 |
Clone | 3B8C1 |
Host Species | Mouse |
Reactive Species | human, nonhuman primate |
Isotype | IgG1 |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:20-1:200, Immunofluorescence: 1:20-1:200, Immunohistochemistry (Paraffin): 1-5 µg/mL, Western Blot: 1:250-1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CYP1A2 Monoclonal Antibody (3B8C1). This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked |
Immunogen | n/a |
Other Names | CP12, P3-450, P450(PA) |
Gene, Accession # | Entrez: 1544; Uniprot: P05177 |
Catalog # | MA3-037 |
Price | |
Order / More Info | CYP1A2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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