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| Product Name | B-Amyloid (1-42), rat |
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| Description | Purity >95%. Abeta 1-42 induces a strong membrane destabilization in giant unilamellar vesicles composed of palmitoyloleoyl-phosphatidylcholine;sphingomyelin;and cholesterol;lowering the critical tension of vesicle rupture. Additionally;Abeta 1-42 triggers the induction of sequential leakage of low- and high-molecular-weight markers trapped inside the giant unilamellar vesicles;but preserving the vesicle shape. The Abeta 1-42 sequence confers particular molecular properties to the peptide that;in turn;influence supramolecular properties associated with membranes that may result in toxicity;including: 1) the ability of the peptide to strongly associate with the membrane;2) a reduction of lateral membrane cohesive forces;and 3) a capacity to break the transbilayer gradient and puncture sealed vesicles. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Abeta 1-42, ratβ-Amyloid Peptide, Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala, b-Amyloid Peptide, bAmyloid Peptide, beta-Amyloid Peptide, betaAmyloid Peptide, βAmyloid Peptide |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H4454 |
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| Price | |
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| Order / More Info | B-Amyloid (1-42), rat from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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