| 产品详情 |
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| Antigenic Specificity | eIF4A2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 0.5-1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | eIF4A2 Polyclonal Antibody. eIF4A2 is a 407 amino acid ATP-dependent RNA helicase belonging to the DEAD box helicase family. It contains one helicase ATP-binding domain and a helicase C-terminal domain. eIF4A2, a subunit of the eIF4F complex, acts as a protein-synthesis initiation factor and thus plays an important role in the binding of mRNA to the 43S pre-initiation complex of ribosomes. Research is carried out to elucidate the potential role of eIF4A2 in glucose homeostasis and also in type 2 diabetes in the presence of metabolic stress where eIF4A2 controls specific mRNA translation and protein synthesis rate in pancreatic beta-cells. Human eIF4A2 interacts with the NS5B protein of Hepatitis C virus (HCV) and facilitates the genomic RNA |
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| Immunogen | n/a |
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| Other Names | BM-010, DDX2B, EIF4A, EIF4F, eIF-4A-II, eIF4A-II, ATP-dependent RNA helicase eIF4A-2, eukaryotic initiation factor 4A-II, eukaryotic translation initiation factor 4A |
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| Gene, Accession # | Entrez: 13682, 1974; Uniprot: P10630, Q14240 |
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| Catalog # | PA5-23260 |
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| Price | |
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| Order / More Info | eIF4A2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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