| 产品详情 |
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| Antigenic Specificity | eIF5A2 |
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| Clone | OTI6G7 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:100, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | eIF5A2 Monoclonal Antibody (OTI6G7). In mammalian cells, translation is controlled at the level of polypeptide chain initiation by eukaryotic initiation factors. The translation initiation factor 5 (eIF5) catalyzes the hydrolysis of GTP bound to the 40S ribosomal subunit, a function necessary for the subsequent joining of the 40S and 60S subunits to form the 80S initiation complex. eIF4E specifically binds to the mRNA cap to promote unwinding and exposure of the AUG-initiation codon. Overexpression of eIF4E can lead to cell transformation and tumorigenesis. An additional initiation factor, eIF2, is present as a heterotrimer composed of eIF2alpha, eIF2beta and eIF2gamma subunits. This heterotrimer forms a complex with GTP and tRNA which then |
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| Immunogen | n/a |
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| Other Names | Eukaryotic translation initiation factor 5A-2; eIF-5A-2; eIF-5A2; Eukaryotic initiation factor 5A isoform 2; EIF5A2 |
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| Gene, Accession # | Entrez: 56648; Uniprot: Q9GZV4 |
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| Catalog # | MA5-26047 |
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| Price | |
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| Order / More Info | eIF5A2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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