产品详情 |
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Antigenic Specificity | OPRK1 (extracellular) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | purified |
Size | 50 µl |
Concentration | lyophilized |
Applications | Western Blot: 1:200-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | OPRK1 (extracellular) Polyclonal Antibody. G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduce |
Immunogen | n/a |
Other Names | kappa-Opioid Receptor (extracellular) |
Gene, Accession # | Entrez: 18387, 29335; Uniprot: P33534, P34975 |
Catalog # | PA5-77568 |
Price | |
Order / More Info | OPRK1 (extracellular) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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