产品详情 |
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Antigenic Specificity | RBL1 |
Clone | KAB6 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RBL1 Monoclonal Antibody (KAB6). p107 is related both in structure and function to the retinoblastoma tumor suppressor protein and p130 (collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p107 converts E2F transcription factors from transcriptional activators to transcriptional repressors. |
Immunogen | n/a |
Other Names | Retinoblastoma related protein |
Gene, Accession # | Entrez: 19650, 5933, 680111; Uniprot: P28749, Q64701 |
Catalog # | MA1-12362 |
Price | |
Order / More Info | RBL1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 23162706 |
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