Edit |   |
Antigenic Specificity | DIO2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DIO2 Polyclonal Antibody. The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine by outer ring deiodination to bioactive 3,3',5-triiodothyronine residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence , which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen | n/a |
Other Names | DIO2; deiodinase; iodothyronine; type II ; 5DII; D2; SelY; TXDI2 ; thyroxine deiodinase; type II; type 2 iodothyronine deiodinase; type II iodothyronine deiodinaseN: type-II 5'deiodinase |
Gene, Accession # | Entrez: 1734; Uniprot: Q92813 |
Catalog # | PA5-65489 |
Price | |
Order / More Info | DIO2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |