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Antigenic Specificity | CD71 (Transferrin Receptor) |
Clone | R17217 (RI7 217.1.4) |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, kappa |
Format | eFluor 450 conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.25 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD71 (Transferrin Receptor) Monoclonal Antibody (R17217 (RI7 217.1.4)), eFluor 450, eBioscience™. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions inclu |
Immunogen | n/a |
Other Names | CD71, T9, TFR, TFR1, TR, TRFR, p90, transferrin receptor protein 1 |
Gene, Accession # | Entrez: 22042; Uniprot: Q62351 |
Catalog # | 48-0711-82 |
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Order / More Info | CD71 (Transferrin Receptor) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 19006485, 25613378, 25615569, 25970251, 26452208, 26527618, 26572749, 27869129, 28123038, 28871080 |
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